Write the following measures in the formula bar:
Large Transactions = CALCULATE( SUM(TransactionData[Revenue]), TransactionData[Revenue] > 10000 )
Large Transactions & Mid_Budget = CALCULATE( SUM(TransactionData[Revenue]), TransactionData[Revenue] > 10000, Advertising[Ad Budget] = "medium" )
Large Transactions & mid_or_small Spend = CALCULATE( SUM(TransactionData[Revenue]), TransactionData[Revenue] > 10000, Advertising[Ad Budget] = "medium" || Advertising[Ad Budget] = "small" )
Since there is a filter on ad budget from the CALCULATE function, the slicer on the report has no effect on the measure. The ad source slicer does change all three measures however, since there was no filter on the ad source column in CALCULATE.